|
|
|
Christof Holliger
|
|
Laboratoire de biotechnologie environnementale
|
Professeur associé
né(e) le: 07.11.1959
nationalité: Suisse
|
bureau(x):
CHC3425
tél: [+41 21 69] 34724,32771,34725
fax: +41-21-6934722
|
|
|
BIOGRAPHY
|
Originaire d'Adliswil, Christof Holliger est né en 1959. Diplômé de l'ETHZ en biologie en 1984, il mène des travaux de recherche dans le domaine de la microbiologie environnementale à l'Université d'Agriculture de Wageningen (Pays-Bas) où il obtient son doctorat en Science de l'environnement en 1992.
En 1992, il retourne en Suisse engagé comme collaborateur scientifique et chef de groupe à l'Institut Fédéral pour l'Aménagement, l'Epuration et la Protection des Eaux (EAWAG) à Kastanienbaum. Il y continue ses recherches sur la déchloruration réductrice, commencées aux Pays-Bas, et dirige des travaux sur la réduction des composés nitroaromatiques, la réduction du fer et la méthanogenèse psychrophile dans les sédiments des lacs. En octobre 1998, il est nommé professeur assistant en biotechnologie environnementale au Département de génie rural de l'EPFL. Ses recherches visent l'application des micro-organismes anaérobies pour le traitement des eaux résiduaires.
En novembre 2004, il est nommé professeur associé et devient responsable du laboratoire de biotechnologie environnementale à la Faculté de l'Environnement naturel, architectural et construit. L'utilisation des techniques de la biologie moléculaire pour la caractérisation des communautés microbiennes impliquées dans le biotraitement de l'air, des eaux et des sols pollués est un outil clé dans les différents projets de recherche visants le développement des nouveaux procédés de traitement.
|
|
MAIN PUBLICATIONS
|
|
|
C. Aeppli, M. Berg, O. A. Cirpka, C. Holliger, R. P. Schwarzenbach, and T. B.
Hofstetter.
Influence of Mass-Transfer Limitations on Carbon Isotope
Fractionation during Microbial Dechlorination of Trichloroethene.
Environmental Science & Technology, 43(23):8813-8820,
2009.
[ Details ]
|
|
|
P. Rossi, F. Gillet, E. Rohrbach, N. Diaby, and C. Holliger.
Statistical assessment of variability of terminal restriction
fragment length polymorphism analysis applied to complex microbial
communities.
Applied and Environmental Microbiology, 75(22):7268-7270,
2009.
[ Details ]
|
|
|
T. H. M. Smits, A. Hüttmann, D. N. Lerner, and C. Holliger.
Detection and Quantification of Bacteria Involved in Aerobic
and Anaerobic Ammonium Oxidation in an Ammonium-Contaminated
Aquifer.
Bioremediation Journal, 13(1):41-51, 2009.
[ Details ]
|
|
|
M. Dadhwal, A. Singh, O. Prakash, S. Gupta, K. Kumari, P. Sharma, S. Jit,
M. Verma, C. Holliger, and R. Lal.
Proposal of biostimulation for hexachlorocyclohexane
(HCH)-decontamination and characterization of culturable bacterial
community from high-dose point HCH-contaminated soils.
Journal of Applied Microbiology, 106(2):381-392, 2009.
[ Details ]
|
|
|
V. Raina, M. Suar, A. Singh, O. Prakash, M. Dadhwal, S. K. Gupta, C. Dogra,
K. Lawlor, S. Lal, J. Roelof van der Meer, C. Holliger, and R. Lal.
Enhanced biodegradation of hexachlorocyclohexane (HCH) in
contaminated soils via inoculation with Sphingobium indicum B90A.
Biodegradation, 19(1):27-40, 2008.
[ Details ]
|
|
|
L. Wick and C. Holliger.
Two-Phase Cultivation Techniques.
In Microbiology of Hydrocarbons, Oils, Lipids and
Derived Compounds. Springer, 2008.
[ Details ]
|
|
|
C. Holliger.
The genus Dehalobacter.
In P. De Vos, G. Garrity, D. Jones, N. Krieg, W. Ludwig, F. Rainey,
K.-H. Schlefer, and W. Whitman, editors, The Bergey's Manual,
volume 3, pages 986-987. Springer, 2008.
[ Details ]
|
|
|
V. Raina, A. Hauser, H.-R. Buser, D. Rentsch, P. Sharma, R. Lal, C. Holliger,
T. Poiger, M. D. Müller, and H.-P. E. Kohler.
Hydroxylated Metabolites of ²- and ´-Hexachlorocyclohexane:
Bacterial Formation, Stereochemical Configuration, and Occurrence
in Groundwater at a Former Production Site.
Environmental Science & Technology, 41(12):4292-4298,
2007.
[ Details ]
|
|
|
N. Diaby, B. Dold, H.-R. Pfeifer, C. Holliger, B. Johnson, and K. Hallberg.
Microbial communities in a porphyry copper tailings impoundment and
their impact on the geochemical dynamics of the mine waste.
Environmental Microbiology, 9(2):298-307, 2007.
[ Details ]
|
|
|
P. Sharma, V. Raina, R. Kumari, S. Malhotra, C. Dogra, H. Kumari, H.-P. E.
Kohler, C. Holliger, and R. Lal.
Haloalkane Dehalogenase LinB is responsible for ²- and
´-hexachlorocyclohexane transoformation in sphingobium indicum B90A.
Applied and Environmental Microbiology, 72(9):5720-5727,
2006.
[ Details ]
|
|
|
R. Pal, S. Bala, M. Dadhwal, M. Kumar, G. Dhingra, O. Prakash, S. Prabagaran,
S. Shiaji, J. Cullum, C. Holliger, and R. Lal.
Hexachlorocyclohexane-degrading bacterial strains Sphingomonas
paucimobilis B90A, UT26 and Sp+, having similar lin genes, represent
three distinct species, Sphingobium indicum sp. nov., sphingobium
japonicum sp. nov. and Sphingobium francense sp. nov., and
reclassification of [Sphingomonas] chungbukensis as Sphingobium
chungbukense comb. nov.
Applied and Environmental Microbiology, 55(5):1965-1972,
2005.
[ Details ]
|
|
|
M. Suar, A. Hauser, T. Poiger, H.-R. Buser, M. D. Müller, C. Dogra, V. Raina,
C. Holliger, J. van der Meer, R. Lal, and H.-P. E. Kohler.
Enantioselective transformation of ±-hexachlorocyclohexane by the
dehydrochlorinases LinA1 and LinA2 from the soil bacterium
Sphingomonas paucimobilis B90A.
Applied and Environmental Microbiology, 71(12):8514-8518,
2005.
[ Details ]
|
|
|
C. Balsiger, C. Holliger, and P. Höhener.
Reductive dechlorination of chlorofluorocarbons and
hydrochlorofluorocarbons in sewage sludge and aquifer sediment microcosms.
Chemosphere, 61(3):361-373, 2005.
[ Details ]
|
|
|
C. Regeard, J. Maillard, C. Dufraigne, P. Deschavanne, and C. Holliger.
Indications for acquisition of reductive dehalogenase genes through
horizontal gene transfer by Dehalococcoides ethenogenes strain 195.
Applied And Environmental Microbiology, 71(6):2955-2961,
2005.
[ Details ]
|
|
|
J. Maillard, C. Regeard, and C. Holliger.
Isolation and characterization of Tn-Dha1, a transposon
containing the tetrachloroethene reductive dehalogenase of
Desulfitobacterium hafniense strain TCE1.
Environmental Microbiology, 7(1):107-117, 2005.
[ Details ]
|
|
|
M. Suar, J. R. van der Meer, M. Lawlor, C. Holliger, and R. Lal.
Dynamics of multiple lin gene expression in Sphingomonas
paucimobilis B90A in response to different hexachlorocyclohexane isomers.
Applied And Environmental Microbiology,
70(11):6650-6656, 2004.
[ Details ]
|
|
|
T. H. M. Smits, C. Devenoges, K. Szynalski, J. Maillard, and C. Holliger.
Development of a real-time PCR method for quantification of the
three genera Dehalobacter, Dehalococcoides, and Desulfitobacterium in
microbial communities.
Journal Of Microbiological Methods, 57(3):369-378, 2004.
[ Details ]
|
|
|
C. Seignez, N. Adler, C. Thoeni, M. Stettler, P. Peringer, and C. Holliger.
Steady-state and transient-state performance of a biotrickling filter
treating chlorobenzene-containing waste gas.
Applied Microbiology And Biotechnology, 65(1):33-37,
2004.
[ Details ]
|
|
|
C. Regeard, J. Maillard, and C. Holliger.
Development of degenerate and specific PCR primers for the
detection and isolation of known and putative chloroethene reductive
dehalogenase genes.
Journal Of Microbiological Methods, 56(1):107-118, 2004.
[ Details ]
|
|
|
C. Dogra, V. Raina, R. Pal, M. Suar, S. Lal, K. H. Gartemann, C. Holliger,
J. R. van der Meer, and R. Lal.
Organization of lin genes and IS6100 among different strains of
hexachlorocyclohexane-degrading Sphingomonas paucimobilis: Evidence for
horizontal gene transfer.
Journal Of Bacteriology, 186(8):2225-2235, 2004.
[ Details ]
|
|
|
J. Maillard, W. Schumacher, F. Vazquez, C. Regeard, W. R. Hagen, and
C. Holliger.
Characterization of the corrinoid iron-sulfur protein
tetrachloroethene reductive dehalogenase of Dehalobacter restrictus.
Applied And Environmental Microbiology, 69(8):4628-4638,
2003.
[ Details ]
|
|
|
A. N. Nozhevnikova, K. Zepp, F. Vazquez, J. B. Zehnder, and C. Holliger.
Evidence for the Existence of Psychrophilic Methanogenic
Communities in Anoxic Sediments of Deep Lakes.
Applied and Environmental Microbiology, (3):1832-1835,
2003.
[ Details ]
|
|
|
C. Holliger, C. Regeard, and G. Diekert.
Dehalogenation by anaerobic bacteria.
In M. Häggblom and I. Bossert, editors, Dehalogenation:
Microbial processes and environmental applications, pages 115-157. Kluwer
Academic Publisher, 2003.
[ Details ]
|
|
|
D. Koné, G. Cissé, C. Seignez, and C. Holliger.
Le lagunage à laitue d'eau (Pistia stratiotes) à Ouagadougou:
une alternative pour l'épuration des eaux usées destinées à l'irrigation.
Cahiers Agricultures, 11:39-43, 2002.
[ Details ]
|
|
|
R. Kumari, S. Subudhi, M. Suar, G. Dhingra, V. Raina, C. Dogra, S. Lal, J. R.
Van der Meer, C. Holliger, and R. Lal.
Cloning and Characterization of lin Genes Responsible for the
Degradation of Hexachlorocyclohexane Ismomers by Sphingomonas
paucimobilis Strain B90.
Applied and Environmental Microbiology, 68(12):6021-6028,
2002.
[ Details ]
|
|
|
D. Koné, G. Cisse, C. Seignez, and C. Holliger.
Le lagunage à macrophytes et l'irrigation en maraîchage: Etude
d'une station expérimentale à Ouagadougou.
Info CREPA, 03 BP 7112 Ouagadougou 03, Burkina Faso,
(31):4, 2001.
[ Details ]
|
|
|
L. Y. Lokshina, V. A. Vavilin, R. H. Kettunen, J. A. Rintala, C. Holliger, and
A. N. Nozhevnikova.
Evaluation of kinetic coefficients using integrated Monod and
Haldane models for low-temperature acetoclastic methanogenesis.
Water Research, 35(12):2913-2922, 2001.
[ Details ]
|
|
|
K. Alha, C. Holliger, B. S. Larsen, P. Purcell, and W. Rauch.
Environmental engineering education - summary report of the 1st
European Seminar.
Water Science and Technology, 41(2):1, 2000.
[ Details ]
|
|
|
K. Zepp Falz, C. Holliger, R. Grosskopf, W. Liesack, A. N. Nozhevnikova,
B. Müller, B. Wehrli, and D. Hahn.
Vertical Distribution of Methanogens in the Anoxic Sediment
of Rotsee (Switzerland).
Applied and Environmental Microbiology, 65(6):2402-2408,
1999.
[ Details ]
|
|
|
C. Holliger, G. Wohlfarth, and G. Diekert.
Reductive dechlorination in the energy metabolism of anaerobic
bacteria.
FEMS Microbiology Reviews, 22:383-398, 1999.
[ Details ]
|
|
|
U. Friedrich, M. Schallenberg, and C. Holliger.
Pelagic Bacteria-Particle Interactions and
Community-Specific Growth Rates in Four Lakes along a Trophic
Gradient.
Microbial Ecology, 37(1):49-61, 1999.
[ Details ]
|
|
|
T. B. Hofstetter, C. G. Heijman, S. B. Haderlein, C. Holliger, and R. P.
Schwarzenbach.
Complete Reduction of TNT and Other (Poly)nitroaromatic
Compounds under Iron-Reducing Subsurface Conditions.
Envrionmental Science & Technology, 33:1479-1487, 1999.
[ Details ]
|
|
|
|
Professeur associé